%0 Journal Article
%T Pioglitazone stabilizes atherosclerotic plaque by regulating the Th17/Treg balance in AMPK-dependent mechanisms
%A Hang Yu
%A Jiahao Feng
%A Juan Zhou
%A Lijun Wang
%A Lin Yang
%A Tao Chen
%A Wei Zhang
%A Xiaojuan Fan
%A Yan Wu
%A Yanjie Yang
%A Yue Wu
%A Yuling Tian
%A Zuyi Yuan
%J Archive of "Cardiovascular Diabetology".
%D 2017
%R 10.1186/s12933-017-0623-6
%X Effects of PIO on Th17/Treg balance and AMPK activation in cultured primary splenocytes. a, b Representative flowcytometric results of Th17 and Treg cells, respectively. Numbers represent the percentage of cells in the quadrants. c, d Quantitative analysis of Th17 and Treg population among the 3 groups respectively. *P < 0.05 vs Con; £¿ P < 0.05 vs ox-LDL. e Representative western blot analysis of pAMPK and AMPK in splenocytes treated with or without ox-LDL and PI
%K Pioglitazone
%K AMPK
%K T cell
%K Signaling
%K Atherosclerosis
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663071/