%0 Journal Article
%T Modulation of doxorubicin-induced expression of the multidrug resistance gene in breast cancer cells by diltiazem and protection against cardiotoxicity in experimental animals
%A Abdel-Moneim M. Osman
%A Ali A. Al Qahtani
%A Hadiah B. Al Mahdi
%A Hamdan S. Al-malky
%A Huda M. Alkreathy
%A Jumana Y. Al Aama
%A Wafaa S. Ramadan
%A Zoheir A. Damanhouri
%J Archive of "Cancer Cell International".
%D 2019
%R 10.1186/s12935-019-0912-0
%X Effect of DOX and/or DIL treatment on cell cycle phase distribution of MCF-7 cells. Cell cycle distribution was analyzed by exposing the cells to drugs for 48 h, then staining with PI. a Control, b cells treated with 20 ¦Ìg/ml DIL, c cells treated with 0.25 ¦Ìg/ml DOX, d cells treated with 0.25 ¦Ìg/ml DOX and 20 ¦Ìg/ml DIL, e cells treated with 1 ¦Ìg/ml DOX, f cells treated with 1 ¦Ìg/ml DOX and 20 ¦Ìg/ml DIL. The experiment was repeated twice each one in duplicat
%K Doxorubicin
%K Diltiazem
%K MCF-7 cells
%K MDR
%K Cardiotoxicity
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657176/