%0 Journal Article %T Weight control interventions improve therapeutic efficacy of dacarbazine in melanoma by reversing obesity-induced drug resistance %A Balkrishna Chaube %A Bipin Gopalakrishnan Nair %A Maleppillil Vavachan Vijayakumar %A Manoj Kumar Bhat %A Muralidharan Vanuopadath %A Naoshad Mohammad %A Parmanand Malvi %A Revathy Meenatheril Radhakrishnan %A Shivendra Vikram Singh %A Sudarslal Sadasivan Nair %A Vimal Pandey %J Archive of "Cancer & Metabolism". %D 2016 %R 10.1186/s40170-016-0162-8 %X Obesity-related cellular, metabolic, and molecular alterations have been shown to increase cancer risk and tumor progression and are associated with poorer therapeutic outcome in cancer patients. However, the impact of obesity and weight-control interventions on the therapeutic response in melanoma is poorly understood %K Obesity %K Adipokines %K Melanoma %K Chemotherapy %K Orlistat %K Weight-control interventions %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142287/