%0 Journal Article %T The Central Role of Endothelial Dysfunction in Cardiorenal Syndrome %A Jun Zhang %A Peter A. McCullough %A Teodoro Bottiglieri %J Archive of "Cardiorenal Medicine". %D 2017 %R 10.1159/000452283 %X Endothelial dysfunction (ED) has emerged as a critical process in cardiorenal syndrome (CRS). The concept that ED is closely linked with cardiac and renal dysfunction has become an important target for CRS-related research and clinical practice %K Angiotensin-converting enzyme inhibitor %K Asymmetric dimethylarginine %K Cardiorenal syndrome %K Endothelial activation %K Type 1 diabetes %K Endothelial dysfunction %K Nitric oxide %K Oxidative stress %K Statins %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465690/