%0 Journal Article
%T DNA damage-induced activation of ATM promotes ¦Â-TRCP-mediated ARID1A ubiquitination and destruction in gastric cancer cells
%A Cai-de Lu
%A Feng Qiu
%A Hai-long Qian
%A Su-zhan Zhang
%A Tao Peng
%A Zhou-hua Jiang
%J Archive of "Cancer Cell International".
%D 2019
%R 10.1186/s12935-019-0878-y
%X ¦Â-TrCP associated with ARID1A. a HEK293T cells were transfected with empty vector (EV) or the indicated FLAG-tagged F-box protein plasmids (FBPs). Cell extracts were immunoprecipitated (IP) with anti-FLAG M2 beads, and the immunocomplexes were subjected to western blot with the indicated antibodies. b HEK293T cells were transfected with Flag-ARID1A for 36 h, cell extracts were IP with anti-FLAG M2 beads, and the immunocomplexes were subjected to western blot with the indicated antibodies. c HEK293T cells were co-transfected with Flag-ARID1A and HA-¦Â-TrCP WT or HA-¦Â-TrCP R474A mutant for 36 h, cell extracts were IP with anti-HA beads, and the immunocomplexes were subjected to western blot with the indicated antibodie
%K ARID1A
%K ¦Â-TRCP
%K Phosphodegron
%K DNA damage
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567580/