%0 Journal Article
%T Application of next-generation sequencing technology to precision medicine in cancer: joint consensus of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology
%A Binghe Xu
%A Cheng Huang
%A Chunyan Wu
%A Gong Chen
%A Hongming Pan
%A Hongxia Tian
%A Hua Bai
%A Hui Li
%A Jianming Ying
%A Jianyong Shao
%A Jie Wang
%A Jinji Yang
%A Jun Hou
%A Li Fu
%A Lin Shen
%A Liwei Wang
%A Mengzhao Wang
%A Ning Liao
%A On behalf of Chinese Society of Clinical Oncology (CSCO) Tumor Biomarker Committee
%A Qing Zhou
%A Qingyuan Zhang
%A Ruibao Ren
%A Ruihua Xu
%A Shengyue Wang
%A Shirong Zhang
%A Shun Lu
%A Suzhan Zhang
%A Tianshu Liu
%A Weiping Liu
%A Wenzhao Zhong
%A Xiaojun Zhou
%A Xiaoqing Liu
%A Xiaoyan Zhou
%A Xiufeng Liu
%A Xuchao Zhang
%A Xuening Yang
%A Yangqiu Li
%A Yanhong Gu
%A Yanhong Tai
%A Yi Liu
%A Yilong Wu
%A Ying Cheng
%A Yingyong Hou
%A Yong Song
%A You Lu
%A Yu Chen
%A Yunpeng Liu
%A Zheng Wang
%A Zhimin Shao
%A Zhiyong Liang
%A Zhongzheng Zhu
%J Archive of "Cancer Biology & Medicine".
%D 2019
%R 10.20892/j.issn.2095-3941.2018.0142
%X Next-generation sequencing (NGS) technology is capable of sequencing millions or billions of DNA molecules simultaneously. Therefore, it represents a promising tool for the analysis of molecular targets for the initial diagnosis of disease, monitoring of disease progression, and identifying the mechanism of drug resistance. On behalf of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology (CSCO) and the China Actionable Genome Consortium (CAGC), the present expert group hereby proposes advisory guidelines on clinical applications of NGS technology for the analysis of cancer driver genes for precision cancer therapy. This group comprises an assembly of laboratory cancer geneticists, clinical oncologists, bioinformaticians, pathologists, and other professionals. After multiple rounds of discussions and revisions, the expert group has reached a preliminary consensus on the need of NGS in clinical diagnosis, its regulation, and compliance standards in clinical sample collection. Moreover, it has prepared NGS criteria, the sequencing standard operation procedure (SOP), data analysis, report, and NGS platform certification and validation
%K Next-generation sequencing technology
%K cancer
%K consensus
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528448/