%0 Journal Article %T Effect of obesity on the effectiveness of cardiac resynchronization to reduce the risk of first and recurrent ventricular tachyarrhythmia events %A Arthur J. Moss %A Barbara Szepietowska %A Bronislava Polonsky %A Mehmet Aktas %A Saadia Sherazi %A Scott McNitt %A Valentina Kutyifa %A Wojciech Zareba %A Yitschak Biton %J Archive of "Cardiovascular Diabetology". %D 2016 %R 10.1186/s12933-016-0401-x %X Obesity is associated with multiple adverse cardiovascular conditions and may increase the risk of ventricular tachyarrhythmias (VT/VF). There is limited data on the association between obesity and risk of VT/VF requiring appropriate implantable cardioverter-defibrillator (ICD) therapies and the effectiveness of cardiac resynchronization therapy (CRT) to reduce risk for VT/VF. The multicenter automatic defibrillator implantation trial with cardiac resynchronization therapy (MADIT-CRT) was design to investigate effectiveness of CRT therapy to reduce cardiovascular outcome for patients with heart failure (HF) and reduced ejection fraction %K Obesity %K Cardiac resynchronization therapy %K Implantable cardioverter defibrillator %K Heart failure %K Ventricular tachyarrhythmias %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936234/