%0 Journal Article
%T SR 11302, an AP-1 Inhibitor, Reduces Metastatic Lesion Formation in Ex Vivo 4D Lung Cancer Model
%A Dhruva Kumar Mishra
%A Min P. Kim
%J Archive of "Cancer Microenvironment".
%D 2017
%R 10.1007/s12307-017-0202-0
%X Relative gene expression (2-¦¤¦¤Ct) of c-Jun and c-Fos genes in primary tumors (PTs), circulatory tumor cells (CTCs), and metastatic lesions (MLs) from a 4D ex vivo lung model seeded with A549 (a & d), H1299 (b & e), and H460 (C & F), cells. a, b, & c c-Jun was significantly upregulated in CTCs as compared to respective PTs for all three-cell lines. d, e & f: c-Fos was significantly upregulated in CTCs as compared to respective PTs and metastatic lesions in all three-cell line
%K Lung cancer
%K Metastasis
%K AP1
%K SR11302
%K 4D lung model
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750205/