%0 Journal Article
%T The role of tumor metabolism as a driver of prostate cancer progression and lethal disease: results from a nested case-control study
%A Andreas Pettersson
%A Edward L. Giovannucci
%A Ericka M. Ebot
%A Howard D. Sesso
%A Jennifer A. Sinnott
%A Jennifer R. Rider
%A Lorelei A. Mucci
%A Massimo Loda
%A Matthew Vander Heiden
%A Michaela Bowden
%A Neil E. Martin
%A Philip W. Kantoff
%A Rachel S. Kelly
%A Svitlana Tyekucheva
%A Travis Gerke
%J Archive of "Cancer & Metabolism".
%D 2016
%R 10.1186/s40170-016-0161-9
%X Understanding the biologic mechanisms underlying the development of lethal prostate cancer is critical for improved therapeutic and prevention strategies. In this study we explored the role of tumor metabolism in prostate cancer progression using mRNA expression profiling of seven metabolic pathways; fatty acid metabolism, glycolysis/gluconeogenesis, oxidative phosphorylation, pentose phosphate, purine metabolism, pyrimidine metabolism and the tricarboxylic acid cycle
%K Prostate cancer
%K mRNA expression profiling
%K Tumor metabolism
%K Metabolomic pathways
%K Tumorigenesis
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142400/