%0 Journal Article
%T Exosomal miRNA-107 induces myeloid-derived suppressor cell expansion in gastric cancer
%A Dai Zhang
%A Hao Rong
%A HuiJie Feng
%A Qian Feng
%A QinXian Zhang
%A ShiChun Tu
%A Wei Wang
%A WeiHong Ren
%A WenBo Li
%A XiaoYan Zhu
%A XuRan Zhang
%A Yan Tong
%A ZhenQiang Zhang
%J Archive of "Cancer Management and Research".
%D 2019
%R 10.2147/CMAR.S198886
%X Background: Myeloid-derived suppressor cells (MDSCs) promote immunosuppression in the tumor microenvironment, support tumor growth and survival, and may contribute to immunotherapy resistance. Recent studies showed that tumor-derived exosomes (TDEs) can induce MDSCs accumulation and expansion, the mechanisms of which are largely unknown
%K exosome
%K miRNA-107
%K myeloid-derived suppressor cell
%K arginase 1
%K gastric cancer
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511657/