%0 Journal Article
%T Expression of insulin receptor (IR) A and B isoforms, IGF-IR, and IR/IGF-IR hybrid receptors in vascular smooth muscle cells and their role in cell migration in atherosclerosis
%A A. G¨®mez-Hern¨¢ndez
%A C. E. Fern¨¢ndez-Garc¨ªa
%A G. Garc¨ªa-G¨®mez
%A J. B. Michel
%A J. Egido
%A J. L. Mart¨ªn-Ventura
%A L. Perdomo
%A M. Benito
%A N. Beneit
%A S. D¨ªaz-Castroverde
%A S. Fern¨¢ndez
%A ¨®. Escribano
%J Archive of "Cardiovascular Diabetology".
%D 2016
%R 10.1186/s12933-016-0477-3
%X Abnormal proliferation and migration of vascular smooth muscle cells (VSMCs) is a major contributor to the development of atherosclerotic process. In a previous work, we demonstrated that the insulin receptor isoform A (IRA) and its association with the insulin-like growth factor-I receptor (IGF-IR) confer a proliferative advantage to VSMCs. However, the role of IR and IGF-IR in VSMC migration remains poorly understood
%K Atherosclerosis
%K Insulin receptor
%K Migration
%K Vascular smooth muscle cells
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134076/