%0 Journal Article
%T Effect of trelagliptin on vascular endothelial functions and serum adiponectin level in patients with type 2 diabetes: a preliminary single-arm prospective pilot study
%A Akihiro Uchida
%A Chiaki Kobayashi
%A Hiroka Takahashi
%A Kanako Imataka
%A Katunori Betou
%A Kazuya Murata
%A Kou Monguchi
%A Ryoko Fujiwara
%A Ryutaro Kaneko
%A Satoshi Ida
%A Yuki Ishihara
%J Archive of "Cardiovascular Diabetology".
%D 2016
%R 10.1186/s12933-016-0468-4
%X Trelagliptin, an oral DPP-4 inhibitor, which is administered once per week and characterized by a long half-life in blood. The effects of trelagliptin on vascular endothelial functions have not been clarified to date. The objective of the present study was to examine the effects of trelagliptin on vascular endothelial functions in patients with type 2 diabetes mellitus (DM) using flow-mediated dilatation (FMD), adiponectin, and asymmetric dimethylarginine (ADMA) as evaluation indicators
%K Type 2 diabetes mellitus
%K Dipeptidyl peptidase-4 inhibitor
%K Trelagliptin
%K Vascular endothelial functions
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096292/