%0 Journal Article
%T Ivabradine Versus Beta-Blockers in Mitral Stenosis in Sinus Rhythm: An Updated Meta-Analysis of Randomized Controlled Trials
%A Elleen L. Cunanan
%A Felix Eduardo R. Punzalan
%A John Daniel A. Ramos
%A Lauro L. Abrahan
%A IV
%A Marc Denver A. Tiongson
%J Archive of "Cardiology Research".
%D 2018
%R 10.14740/cr737w
%X Symptoms of mitral stenosis (MS) are worsened during tachycardia and exercise. Beta-blockers are used in controlling heart rate (HR) in MS, resulting in symptom improvement, but coming with significant side effects. Ivabradine has a selective action on the sinus node devoid of the usual side effects of beta-blockers. Small studies have recently investigated the role of ivabradine in MS in sinus rhythm. Our aim was to determine the efficacy of ivabradine, compared to beta-blockers, in terms of exercise duration, maximum HR achieved, resting HR, mean gradient, and working capacity among patients with MS in sinus rhythm
%K Ivabradine
%K Mitral stenosis
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089474/