%0 Journal Article %T Implementation of staging systems in clinical practice for cutaneous squamous cell carcinoma %A Javier Ca£¿ueto %J Archive of "Annals of Translational Medicine". %D 2019 %R 10.21037/atm.2019.03.13 %X Staging systems have been poorly implemented in clinical practice in cutaneous squamous cell carcinoma (CSCC) mainly because guidelines have been essentially based on risk factors rather than in T stage itself. However, its extensive use would be desirable in patient¡¯s management. Forty years after the publication of the First edition of the American Joint Committee on Cancer (AJCC) Staging System, the Eight edition (AJCC-8) was recently published with relevant changes in skin cancer (1), including CSCC. The AJCC-8 considers T1 a CSCC <2 cm of horizontal size, T2 a tumor ¡Ư2 cm up to 4 cm and T3 a tumor ¡Ư4 cm. Also, the AJCC-8 considers T3 a tumor with a thickness >6 mm, with perineural invasion (of nerves ¡Ư0.1 mm or of nerves deeper than the dermis) and when slight bone erosion exists. A CSCC is classified as T4 if extensive bone invasion exists or when invasion through the foramen of the skull is developed %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462593/