%0 Journal Article %T NEUROENDOCRINE DIFFERENTIATION IN INVASIVE LOBULAR BREAST CARCINOMA %A H. Bumbea %A M. Stoicea %A M.C. Onisai %A S.E. Gradinaru %J Archive of "Acta Endocrinologica (Bucharest)". %D 2017 %R 10.4183/aeb.2017.246 %X Neuroendocrine differentiation is a form of immunophenotypical metaplasia encountered in tumors lacking neuroendocrine morphological features, especially high grade carcinomas of cohesive types, including up to 18% of breast carcinomas. Neuroendocrine type is exceedingly rare encountered in discohesive lobular breast carcinomas, as few case reports indicate (1-3). In most cases, neuroendocrine differentiation occurred in less than 50% of the tumor cells %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516445/