%0 Journal Article
%T Fibroblastic Polyps: A Novel Polyp Subtype in Cowden Syndrome
%A Bradley Anderson
%A Seth Sweester
%A Thomas Smyrk
%J Archive of "ACG Case Reports Journal".
%D 2017
%R 10.14309/crj.2017.113
%X Cowden syndrome (CS) represents one possible phenotype of the PTEN gene mutation, and it can cause hamartomas throughout the gastrointestinal tract, with a predisposition for malignancy. Fibroblastic polyps have not been associated with CS. A 45-year-old woman with CS presenting for colonoscopic surveillance was found to have multiple sessile polyps throughout the transverse, descending, and sigmoid colon, all 2¨C5 mm in diameter. Based on the morphologic features and the immunohistochemical profile, these lesions were classified as fibroblastic polyps. This polyp subtype is recognized as a benign process of the colonic mucosa but is a novel histologic observation in the setting of CS
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636907/