%0 Journal Article
%T Discovery of IWP-051, a Novel Orally Bioavailable
sGC Stimulator with Once-Daily Dosing Potential in Humans
%A Andrew Carvalho
%A Angelika Fretzen
%A Charles Kim
%A Chrissie Segal
%A Daniel P. Zimmer
%A Erik O. Solberg
%A G-Yoon J. Im
%A Hong Jin
%A Jason M. Rohde
%A Jenny Tobin
%A Joel Moore
%A Kimberly Long
%A Mark G. Currie
%A Nicholas R. Perl
%A Peter Germano
%A Renee Sarno
%A Takashi Nakai
%A Thomas W.-H. Lee
%A Timothy C. Barden
%J Archive of "ACS Medicinal Chemistry Letters".
%D 2016
%R 10.1021/acsmedchemlett.5b00479
%K Soluble guanylate cyclase
%K sGC
%K NO-independent stimulators
%K heme-dependent sGC stimulators
%K nitric oxide
%K IWP-051
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867485/