%0 Journal Article %T New Substituted Cyanoindoline Derivatives as MAP3K14 Kinase Inhibitors for the Treatment of Cancer and Autoimmune Disorders %A Robert B. Kargbo %J Archive of "ACS Medicinal Chemistry Letters". %D 2017 %R 10.1021/acsmedchemlett.7b00330 %X The NIK/MAP3K14 autophosphorylation activity was measured using the Alpha Screen (¦Áscreen) format (PerkinElmer). The compounds were tested for inhibition of the autophosphorylation of recombinant human NF-kappaB-inducing kinase (NIK/MAP3K14) activity. Assays were carried out in 384-well Alphaplates (PerkinElmer) %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601364/