%0 Journal Article
%T GluN2A-Selective Pyridopyrimidinone Series of NMDAR
Positive Allosteric Modulators with an Improved in Vivo Profile
%A Aijun Lu
%A Benjamin D. Sellers
%A Bianca M. Liederer
%A Cuong Q. Ly
%A David H. Hackos
%A Elisia Villemure
%A Emile Plise
%A Gauri Deshmukh
%A Guosheng Wu
%A Heidi J. A. Wallweber
%A Jacob B. Schwarz
%A Jesse
E. Hanson
%A Kimberly Scearce-Levie
%A Matthew Volgraf
%A Mingcui Liu
%A Patrick
J. Lupardus
%A Po-wai Yuen
%A Shun Zhang
%A Suzanne Tay
%A Tzu-Ming Wang
%A Xifeng Luo
%A Yu Jiang
%J Archive of "ACS Medicinal Chemistry Letters".
%D 2017
%R 10.1021/acsmedchemlett.6b00388
%K NMDAR
%K PAM
%K AMPAR
%K allosteric
%K potentiator
%K selectivity
%K brain concentration
%K CNS
%K EPSP
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238474/