%0 Journal Article
%T Hepatitis C Virus-Associated Aortitis Caused by Type I Cryoglobulins
%A Adrienne Lenhart
%A Alireza Meighani
%A Mona Hassan
%A Stuart Gordon
%J Archive of "ACG Case Reports Journal".
%D 2017
%R 10.14309/crj.2017.114
%X Chronic hepatitis C virus infection (HCV) can present with cryoglobulinemic vasculitis, which is primarily associated with type II/III cryoglobulins. Type I cryoglobulins are usually seen in lymphoproliferative disease, and large vessel involvement with this type of vasculitis is rare. A 70-year-old man with chronic HCV presented with abdominal pain, leukocytosis, and rash. Computed tomography angiography showed thickening of the abdominal aorta consistent with large-vessel vasculitis. He was found to have type I cryoglobulinemia and was treated with corticosteroids and ledipasvir/sofosbuvir with rapid resolution of his aortitis. This case emphasizes the need to recognize HCV as a potential etiology of large-vessel vasculitis
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658650/