%0 Journal Article
%T Infliximab-Induced Aseptic Meningitis in a Patient with Crohn¡¯s Disease
%A Brett Theeler
%A Manish Singla
%A Zachary Junga
%J Archive of "ACG Case Reports Journal".
%D 2018
%R 10.14309/crj.2018.48
%X Infliximab is an anti-tumor necrosis factor ¦Á (TNF¦Á) monoclonal antibody that treats moderate-to-severe Crohn¡¯s disease. In rare cases, infliximab has been associated with drug-induced aseptic meningitis. We present a 46-year-old woman with migraines and inflammatory Crohn¡¯s colitis treated with intravenous infliximab and methotrexate. She developed nuchal rigidity, photophobia, and headache 2 days after each of her infliximab infusions, with symptom resolution 1 week post-infusion. Her exam, imaging, and cerebrospinal fluid analysis were consistent with drug-induced aseptic meningitis. She discontinued infliximab and started vedolizumab with continued remission of her Crohn¡¯s disease
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013687/