%0 Journal Article %T Treatment and clinical outcome of clinical T4 esophageal cancer: A systematic review %A Kiyokazu Nakajima %A Koji Tanaka %A Makoto Yamasaki %A Masaaki Motoori %A Masaki Mori %A Tsuyoshi Takahashi %A Yasuhiro Miyazaki %A Yuichiro Doki %A Yukinori Kurokawa %A Yutaka Kimura %J Archive of "Annals of Gastroenterological Surgery". %D 2019 %R 10.1002/ags3.12222 %X Survival of patients with cT4 esophageal cancer is dismal. Although the optimal treatment strategy remains to be established, two treatment options are available for cT4 esophageal cancers: definitive chemoradiation (dCRT) and induction treatment followed by conversion surgery (CS). However, little is known concerning the differences in clinical outcome between patients with T4 esophageal tumors treated with dCRT and those eventually treated with CS %K conversion surgery %K definitive chemoradiation %K esophageal cancer %K induction chemotherapy %K T4 %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422802/