%0 Journal Article
%T Phenotypic and genetic changes in the life cycle of small colony variants of Salmonellaenterica serotype Typhimurium induced by streptomycin
%A Qian Zhang
%A Qiongcheng Chen
%A Qun Sun
%A Wanli Li
%A Xiaolu Shi
%A Yao Liu
%A Yarong Wu
%A Yinghui Li
%A Yujun Cui
%J Archive of "Annals of Clinical Microbiology and Antimicrobials".
%D 2016
%R 10.1186/s12941-016-0151-3
%X Small colony variants (SCVs), constituting a slow-growing subpopulation of bacteria that facilitates persistence in lethal environmental conditions, are able to revert to the phenotype of rapid growth for further proliferation and transmission. Salmonella enterica serotype Typhimurium is one of the most important foodborne pathogens. This study investigated the genetic mechanisms how SCVs induced by streptomycin reverted to the fast-growing phenotype and the phenotypic changes of SCVs among their complete life cycle in S.Typhimurium
%K Small colony variants
%K Salmonella
%K Biofilm
%K ubiE
%K prfB
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888536/