%0 Journal Article
%T The association of paraoxonase 1 gene L55M polymorphism with the extent and severity of coronary artery disease in the Turkish population and its dependence on gender
%A Derya Beyza Say£¿n Kocakap
%A Feryal £¿abuk
%A Mehmet Tolga Do£¿ru
%A Neslig¨¹l Y£¿ld£¿r£¿m
%A Sibel Aly£¿lmaz Bekmez
%A Solmaz Erdem
%A Vedat £¿im£¿ek
%A Yunus £¿elik
%J Archive of "Anatolian Journal of Cardiology".
%D 2016
%R 10.5152/akd.2015.6010
%X Coronary artery disease (CAD) is a common, complex, and progressive disorder characterized by the accumulation of lipids and fibrous elements in the arteries. It is one of the leading causes of death in industrialized nations. Oxidative modification of low-density lipoprotein (LDL) in the arterial wall plays an important role in the initiation and progression of atherosclerosis. Paraoxonase1 (PON1) is involved in lipid metabolism and is believed to protect LDL oxidation. In our study, we aimed to clarify the relationship between PON1 gene L55M polymorphism and the extent and severity of CAD
%K paraoxonase1
%K coronary artery disease
%K atherosclerosis
%K L55M polymorphism
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336803/