%0 Journal Article
%T Dysregulated lipid storage and its relationship with insulin resistance and cardiovascular risk factors in non-obese Asian patients with type 2 diabetes
%A Chatchalit Rattarasarn
%J Archive of "Adipocyte".
%D 2018
%R 10.1080/21623945.2018.1429784
%X The prevalence of non-obese type 2 diabetes in Asians is up to 50%. This review aims to summarize the role of regional fat in the development of insulin resistance and cardiovascular risk in non-obese Asian type 2 diabetes as well as the role of intra-pancreatic fat and ¦Â-cell dysfunction. The body fat content of non-obese Asian type 2 diabetic patients is not different from that of non-diabetic subjects but the proportion of intra-abdominal and intra-hepatic fat are greater. Visceral fat contributes to insulin resistance and cardiovascular risk in non-obese Asian type 2 diabetes. Intra-hepatic fat and the hypertrophic abdominal subcutaneous adipocytes are associated with insulin resistance and cardiovascular risk in non-obese, non-diabetic Asian subjects. It may be true in non-obese Asian type 2 diabetic patients. The role of intra-myocellular lipid and insulin resistance is uncertain. Intra-pancreatic fat may not be involved in ¦Â-cell dysfunction in non-obese Asian type 2 diabetes
%K type 2 diabetes
%K non-obese
%K subcutaneous fat
%K abdominal subcutaneous fat
%K visceral fat
%K intra-hepatic fat
%K intra-myocellular lipid
%K intra-pancreatic fat
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152525/