%0 Journal Article
%T Moderate intensity physical activity associates with CSF biomarkers in a cohort at risk for Alzheimer's disease
%A Barbara B. Bendlin
%A Bruce P. Hermann
%A Catherine L. Gallagher
%A Cynthia M. Carlsson
%A Dane B. Cook
%A Dorothy F. Edwards
%A Henrik Zetterberg
%A Kaj Blennow
%A Lena L. Law
%A Mark A. Sager
%A Rachael N. Rol
%A Rebecca L. Koscik
%A Ryan J. Dougherty
%A Sanjay Asthana
%A Stephanie A. Schultz
%A Sterling C. Johnson
%J Archive of "Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring".
%D 2018
%R 10.1016/j.dadm.2018.01.001
%X Alzheimer's disease (AD) is characterized by the presence of amyloid ¦Â (A¦Â) plaques, neurofibrillary tangles, and neurodegeneration, evidence of which may be detected in vivo via cerebrospinal fluid (CSF) sampling. Physical activity (PA) has emerged as a possible modifier of these AD-related pathological changes. Consequently, the aim of this study was to cross-sectionally examine the relationship between objectively measured PA and CSF levels of A¦Â42 and tau in asymptomatic late-middle-aged adults at risk for AD
%K Alzheimer's disease
%K CSF biomarkers
%K Exercise
%K Physical activity
%K Sedentary behavior
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842318/