%0 Journal Article
%T Tolerability of ORM-12741 and effects on episodic memory in patients with Alzheimer's disease
%A Henry Riordan
%A Hilkka Soininen
%A Jeffrey L. Cummings
%A Juha O. Rinne
%A Jutta H£¿nninen
%A Keith Wesnes
%A Merja Hallikainen
%A Michael Murphy
%A Mika Scheinin
%A Pasi Hakulinen
%J Archive of "Alzheimer's & Dementia : Translational Research & Clinical Interventions".
%D 2017
%R 10.1016/j.trci.2016.11.004
%X ORM-12741 is a novel selective antagonist of alpha-2C adrenoceptors. This trial evaluated the safety and efficacy of ORM-12741 in patients with Alzheimer's disease (AD)
%K Alzheimer's disease
%K Cognition
%K Memory
%K Alpha-2C adrenoceptor antagonist
%K ORM-12741
%K Randomized trials
%K Behavioral and psychological symptoms of dementia
%K Neuropsychiatric symptoms
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651366/