%0 Journal Article
%T Zfra restores memory deficits in Alzheimer's disease triple-transgenic mice by blocking aggregation of TRAPPC6A¦¤, SH3GLB2, tau, and amyloid ¦Â, and inflammatory NF-¦ÊB activation
%A Chun-I Sze
%A Ming-Hui Lee
%A Nan-Shan Chang
%A Sing-Ru Lin
%A Yao-Hsiang Shih
%A Yu-Hao Lin
%A Yu-Min Kuo
%J Archive of "Alzheimer's & Dementia : Translational Research & Clinical Interventions".
%D 2017
%R 10.1016/j.trci.2017.02.001
%X Zinc finger-like protein that regulates apoptosis (Zfra) is a naturally occurring 31-amino-acid protein. Synthetic peptides Zfra1¨C31 and Zfra4¨C10 are known to effectively block the growth of many types of cancer cells
%K Zfra
%K TRAPPC6A
%K SH3GLB2
%K WWOX
%K Peptide polymerization
%K Protein degradation
%K Neurodegeneration
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651433/