%0 Journal Article %T Proton pump inhibitors and the risk of severe cognitive impairment: The£¿role of posttraumatic stress disorder %A Benjamin J. Luft %A Evelyn J. Bromet %A Lan Lei %A Monika Waszczuk %A Oren Shapira %A Roman Kotov %J Archive of "Alzheimer's & Dementia : Translational Research & Clinical Interventions". %D 2017 %R 10.1016/j.trci.2017.08.007 %X Proton pump inhibitors (PPIs), a common treatment for gastroesophageal reflux disease (GERD), were recently associated with increased risk of dementia. However, severe or chronic stress including, for example, posttraumatic stress disorder (PTSD) was not accounted for. This study examined whether PPI use was associated with severe cognitive impairment (SCI) and whether PTSD explained this association in a cohort of World Trade Center (WTC) responders %K Cognitive impairment %K Proton pump inhibitors %K Posttraumatic stress disorder %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671627/