%0 Journal Article %T Motor Recovery after Transplantation of Bone Marrow Mesenchymal Stem Cells in Rat Models of Spinal Cord Injury %A George Tharion %A Indirani Kanakasabapathy %A Praghalathan Kanthakumar %J Archive of "Annals of Neurosciences". %D 2019 %R 10.1159/000487069 %X Neuronal tissue has a limited potential to self-renew or get repaired after damage. Cell therapies using stem cells are promising approaches for the treatment of central nervous system (CNS) injuries. However, the clinical use of embryonic stem cells is limited by ethical concerns and other scientific consequences. Bone marrow mesenchymal stromal cells (BM-MSC) could represent an alternative source of stem cells for replacement therapy. Indeed, many studies have demonstrated that MSCs can give rise to neuronal cells as well as many tissue-specific cell phenotypes %K Spinal cord injury %K Mesenchymal stem cells %K Transplantation %K Basso %K Beattie %K Bresnahan score %K Electromyography %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388433/