%0 Journal Article
%T Effects of Long-Term Dietary Protein Restriction on Intestinal Morphology, Digestive Enzymes, Gut Hormones, and Colonic Microbiota in Pigs
%A Defu Yu
%A Weiyun Zhu
%J Archive of "Animals : an Open Access Journal from MDPI".
%D 2019
%R 10.3390/ani9040180
%X In China, a shortage of protein resources is an important limiting factor to the economic benefit of pig production, and the use of protein-restriction diets balanced with amino acids is an effective strategy to save protein resources. However, long-term protein-restriction diets can impair the growth performance, and the reason is still unknown. This study is to investigate the response of gastrointestinal physiology and gut microbiota to the condition of long-term low-protein diet and to try to provide a theoretical foundation for better use of protein resources in swine production. Results showed that presented with moderate protein-restriction diets, pigs are able to adjust their absorption and consumption of nutrients to maintain growth performance; whereas extremely low-protein diets suppress pigsĄ¯ appetite, impair intestinal morphology, decrease Lactobacillus and Streptococcus, and reduce energy expenditure. Thus, moderate reduction of dietary protein is more suitable for pig production than extremely low-protein diets supplemented with essential amino acids, and moderate protein-restriction diets can potentially increase protein utilization in pig production
%K pigs
%K low-protein diet
%K digestive enzymes
%K intestinal morphology
%K gut hormone
%K colonic microbiota
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523122/