%0 Journal Article %T Leveraging Terminology Services for Extract-Transform-Load Processes: A User-Centered Approach %A Guoqian Jiang %A Hongfang Liu %A Kevin J. Peterson %A Scott M. Brue %J Archive of "AMIA Annual Symposium Proceedings". %D 2016 %X Terminology services serve an important role supporting clinical and research applications, and underpin a diverse set of processes and use cases. Through standardization efforts, terminology service-to-system interactions can leverage well-defined interfaces and predictable integration patterns. Often, however, users interact more directly with terminologies, and no such blueprints are available for describing terminology service-to-user interactions. In this work, we explore the main architecture principles necessary to build a user-centered terminology system, using an Extract-Transform-Load process as our primary usage scenario. To analyze our architecture, we present a prototype implementation based on the Common Terminology Services 2 (CTS2) standard using the Patient-Centered Network of Learning Health Systems (LHSNet) project as a concrete use case. We perform a preliminary evaluation of our prototype architecture using three architectural quality attributes: interoperability, adaptability and usability. We find that a design-time focus on user needs, cognitive models, and existing patterns is essential to maximize system utility %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333225/