%0 Journal Article
%T Expression Analysis of IZUMO1 Gene during Testicular Development of Datong Yak (Bos Grunniens)
%A Anum Ali Ahmad
%A Min Chu
%A Pengjia Bao
%A Qudratullah Kalwar
%A Xiaoyun Wu
%A Xuezhi Ding
%J Archive of "Animals : an Open Access Journal from MDPI".
%D 2019
%R 10.3390/ani9060292
%X IZUMO1 (IZUMO sperm-egg fusion) is a crucial member of the immunoglobulin superfamily, and it plays a vital part in egg sperm interaction, fusion, and in spermatogenesis. Previous studies identified the fundamental role of the IZUMO1 gene in meiosis of bovine spermatogenesis and spermatogenic cell development and fertility. The current study confirmed the significant expression of the IZUMO1 gene with testicular development and its potential role in fertilization of Datong yak. This research explained the biological role of IZUMO1 in yak reproduction; therefore in the future it might provide a novel prospect to apply data on reproduction and to understand the further regulatory mechanisms of the IZUMO1 gene during spermatogenesis of different mammalian species
%K Datong yak
%K fertilization
%K IZUMO1
%K testis
%K testicular development
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616492/