%0 Journal Article
%T Multiple comorbid neuropathologies in the setting of Alzheimer's disease neuropathology and implications for drug development
%A Christopher Randolph
%A David S. Knopman
%A David S. Miller
%A Eric E. Smith
%A Gil D. Rabinovici
%A John R. Sims
%A Lisa J. Bain
%A Maria C. Carrillo
%A Maria Isaac
%A Mark Forman
%A Nicholas Kozauer
%A Niklas Mattsson
%A Ronald C. Petersen
%A Susan DeSanti
%J Archive of "Alzheimer's & Dementia : Translational Research & Clinical Interventions".
%D 2017
%R 10.1016/j.trci.2016.09.002
%X Dementia is often characterized as being caused by one of several major diseases, such as Alzheimer's disease (AD), cerebrovascular disease, Lewy body disease, or a frontotemporal degeneration. Failure to acknowledge that more than one entity may be present precludes attempts to understand interactive relationships. The clinicopathological studies of dementia demonstrate that multiple pathologic processes often coexist
%K Alzheimer's disease (AD)
%K Cerebrovascular disease
%K Lewy body disease
%K Frontotemporal degeneration
%K ¦Â-amyloid
%K Tau
%K ¦Á-Synuclein
%K TDP-43
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651346/