%0 Journal Article %T NGP 555, a ¦Ã-secretase modulator, lowers the amyloid biomarker, A¦Â42, in cerebrospinal fluid while preventing Alzheimer's disease cognitive decline in rodents %A Courtney Lane-Donovan %A Dan W. Nowakowski %A Joachim Herz %A William T. Comer %J Archive of "Alzheimer's & Dementia : Translational Research & Clinical Interventions". %D 2017 %R 10.1016/j.trci.2016.09.003 %X Alzheimer's disease (AD) is defined by the progressive accumulation of amyloid plaques and neurofibrillary tangles in the brain which precedes cognitive decline by years %K Alzheimer's %K Amyloid %K Modulator %K Biomarkers %K Pathology %K Prevention %K Cognition %K Cerebrospinal fluid %K Dementia %K Gamma-secretase %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421551/