%0 Journal Article
%T The effects of apolipoprotein E genotype, ¦Á-synuclein deficiency, and sex on brain synaptic and Alzheimer's disease¨Crelated pathology
%A Anat Boehm-Cagan
%A Ishai Luz
%A Roni Bar
%A Yarden Kleper-Wall
%J Archive of "Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring".
%D 2018
%R 10.1016/j.dadm.2017.08.003
%X Alzheimer's disease (AD) and synucleinopathies share common pathological mechanisms. Apolipoprotein E4 (apoE4), the most prevalent genetic risk factor for AD, also increases the risk for dementia in pure synucleinopathies. We presently examined the effects of ¦Á-synuclein deficiency (¦Á-syn£¿/£¿) and sex on apoE4-driven pathologies
%K Alzheimer's disease
%K Apolipoprotein E4 (apoE4)
%K apoE-targeted replacement mice
%K Sex
%K ¦Á-Synuclein deficiency
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678739/