%0 Journal Article %T Frontotemporal dementia is the leading cause of ¡°true¡± A£¿/T+ profiles defined with A¦Â42/40 ratio %A Claire Boutoleau-Bretonni¨¨re %A Claire Paquet %A Edith Bigot-Corbel %A Elodie Bouaziz-Amar %A Emilie Skrobala %A Florence Pasquier %A H¨¦l¨¨ne Pouclet-Courtemanche %A Julien Dumurgier %A Susanna Schraen %A Tri-Bao Nguyen %J Archive of "Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring". %D 2019 %R 10.1016/j.dadm.2019.01.001 %X Patients with positive tauopathy but negative A¦Â42 (A£¿T+) in the cerebrospinal fluid (CSF) represent a diagnostic challenge. The A¦Â42/40 ratio supersedes A¦Â42 and reintegrates ¡°false¡± A£¿T+ patients into the Alzheimer's disease spectrum. However, the biomarker and clinical characteristics of ¡°true¡± and ¡°false¡± A£¿T+ patients remain elusive %K Alzheimer's disease %K Cerebrospinal fluid biomarkers %K A¦Â42/40 ratio %K A¦Â42/A¦Â40 ratio %K Frontotemporal dementia %K Suspected non Alzheimer's disease pathology (SNAP) %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378630/