%0 Journal Article %T Elevated Inflammatory Status and Increased Risk of Chronic Disease in Chronological Aging: Inflamm-aging or Inflamm-inactivity? %A Andres E. Carrillo %A Melissa M. Markofski %J Archive of "Aging and Disease". %D 2019 %R 10.14336/AD.2018.0326 %X Age-associated hyper-inflammation or ¡°inflamm-aging¡± has been linked to the development of chronic diseases and characterized as an unavoidable aspect of aging. However, the inflamm-aging model does not adequately address the potential anti-inflammatory effects of exercise training and the potential for exercise to ameliorate several age-related diseases. In this brief review, we introduce a new paradigm¡ªinflamm-inactivity¡ªthat describes a potent counter-measure to age-associated inflammatory illness %K inflammation %K exercise %K physical activity %K immune system %K gerontology %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345337/