%0 Journal Article
%T Field size effects on the risk and severity of treatment-induced lymphopenia in patients undergoing radiation therapy for solid tumors
%J Archive of "Advances in Radiation Oncology".
%D 2018
%R 10.1016/j.adro.2018.08.014
%X Radiation-induced lymphopenia (RIL) is the result of direct toxicity to circulating lymphocytes as they traverse the irradiated field, occurs in 40% to 70% of patients who undergo conventional external beam radiation therapy, and is associated with worse outcomes in multiple solid tumors. As immunotherapy strategies evolve, a better understanding of radiation's effects on the immune system is needed in order to develop rational methods of combining RT with immunotherapy
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200885/