%0 Journal Article
%T A Reversibly Responsive Fluorochromic Hydrogel Based on Lanthanide¨CMannose Complex
%A Chi Yao
%A Ke Meng
%A Qianmin Ma
%A Wenguang Liu
%A Yaping Du
%A Zhaohui Xue
%J Archive of "Advanced Science".
%D 2019
%R 10.1002/advs.201802112
%X Fluorochromic materials that are dynamic in response to external stimuli are of great interest for the development of advanced sensors and luminescent materials. Herein, a design based on a lanthanide©\containing polymeric hydrogel possessing characteristic emission of lanthanides (Eu and Tb) and showing response to stimuli of metal ions is reported. The fluorochromic hydrogel is prepared using a lanthanide¨Cmannose complex in gelation matrix. The lanthanide¨Cmannose complex shows tunable fluorescent emission in response to Fe2+, due to the inhibition of the ¡°antenna effect¡± between metal ions and ligands upon stimulation. The fluorescent hydrogel shows reversible ¡°On/Off¡± fluorochromic response to Fe2+/ethylenediaminetetraacetic acid (EDTA). Remarkably, the fluorescent hydrogel is proven nontoxic and biocompatible; and a proof©\of©\application as in situ 3D cell culture extracellular matrix with reversible fluorochromic ¡°On/Off¡± switch upon Fe2+/EDTA is demonstrated. This reversibly responsive fluorochromic hydrogel demonstrates a way to fabricate smart optical materials, particularly for biological©\related applications where reversible response is required
%K 3D cell culture
%K fluorochromic materials
%K hydrogels
%K lanthanide¨Cmannose complex
%K responsive materials
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523369/