%0 Journal Article
%T Genome-Wide Profiling of the Microrna Transcriptome Regulatory Network to Identify Putative Candidate Genes Associated with Backfat Deposition in Pigs
%A Fuping Zhao
%A Hongmei Gao
%A Hua Yan
%A Jianfei Gong
%A Lixian Wang
%A Longchao Zhang
%A Xin Liu
%A Xinhua Hou
%J Archive of "Animals : an Open Access Journal from MDPI".
%D 2019
%R 10.3390/ani9060313
%X Backfat thickness is an important characteristic in pig breeding. In this study, the key microRNAs (miRNAs) and genes associated with pig backfat deposition were detected and characterized using RNA sequencing between adipose tissues of high-backfat and low-backfat pigs. Strong candidate mRNA£żmiRNA interaction pairs were identified to affect backfat deposition through the regulation of target genes by miRNAs. These results provide novel insights into the backfat deposition mechanism in pigs
%K backfat deposition
%K candidate gene
%K expression profile
%K pig
%K regulatory network
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617047/