%0 Journal Article %T Revisiting Oxidative Stress and the Use of Organic Selenium in Dairy Cow Nutrition %A Darren T. Juniper %A Ivan I. Kochish %A Peter F. Surai %A Vladimir I. Fisinin %J Archive of "Animals : an Open Access Journal from MDPI". %D 2019 %R 10.3390/ani9070462 %X Among feed-derived antioxidants, selenium (Se) was shown to have a special place as an essential part of 25 selenoproteins identified in animals. Organic Se, in the form of selenomethionine (SeMet), has been reported to be a much more effective Se source when compared with mineral forms such as sodium selenite or selenate. There is a growing body of evidence that demonstrates that organic Se has a number of benefits, particularly in dairy and beef animals; these include improved selenium and antioxidant status, and better Se transfer via the placenta, colostrum, and milk to the newborn. However, there is a paucity in the data concerning molecular mechanisms of SeMet assimilation, metabolism and selenoprotein synthesis regulation in ruminant animals, and as such, further investigation is required %K oxidative stress %K organic selenium %K nutrition %K dairy %K antioxidant %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680431/