%0 Journal Article
%T Seizures associated with low-dose tramadol for chronic pain treatment
%A Ali Fuat Erdem
%A Fikret Bayar
%A Serb¨¹lent G£¿khan Beyaz
%A Tu£¿ba Sonbahar
%J Archive of "Anesthesia, Essays and Researches".
%D 2016
%R 10.4103/0259-1162.177181
%X The management of cancer pain still poses a major challenge for clinicians. Tramadol is a centrally acting synthetic opioid analgesic. Its well-known side effects include nausea, vomiting, and dizziness; seizures are a rare side effect. Some reports have found that tramadol triggers seizure activity at high doses, whereas a few preclinical studies have found that this seizure activity is not dose-related. We herein present a case involving a patient with laryngeal cancer who developed seizures while on low-dose oral tramadol
%K Cancer
%K low dose
%K pain
%K seizures
%K tramadol
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864678/