%0 Journal Article
%T The TNBS-induced colitis animal model: An overview
%A Anastasia Pikouli
%A Anastasios Angelou
%A Apostolos Papalois
%A Efstathios Antoniou
%A Emmanouil Pikoulis
%A Georgios Antonios Margonis
%A Ioannis Karavokyros
%A Paraskevi Argiri
%J Archive of "Annals of Medicine and Surgery".
%D 2016
%R 10.1016/j.amsu.2016.07.019
%X Despite recent advances the pathogenesis of Crohn's disease remains incompletely understood. A variety of animal models have been utilized in an effort to provide further insights and develop more therapeutic options. In order to simulate, to an extent, the pathogenesis and the clinical course of the disease, TNBS induced colitis is often used. Various approaches for inducing TNBS -colitis have been described in the literature
%K TNBS
%K Colitis
%K Crohn's disease
%K Animal model
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021709/