%0 Journal Article
%T Early affective changes and increased connectivity in preclinical Alzheimer's disease
%A Alice Y. Hua
%A Dean F. Wong
%A Jesse A. Brown
%A Murat Bilgel
%A Susan M. Resnick
%A Virginia E. Sturm
%A William W. Seeley
%J Archive of "Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring".
%D 2018
%R 10.1016/j.dadm.2018.06.002
%X Affective changes precede cognitive decline in mild Alzheimer's disease and may relate to increased connectivity in a ˇ°salience networkˇ± attuned to emotionally significant stimuli. The trajectory of affective changes in preclinical Alzheimer's disease, and its relationship to this network, is unknown
%K Amyloid-PET
%K Alzheimer's disease
%K Preclinical Alzheimer's disease
%K Neuropsychiatric symptoms
%K Functional connectivity
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174255/