%0 Journal Article %T LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity %A Binghui Li %A Cheryl H. Arrowsmith %A Dalia Barsyte-Lovejoy %A Ernesto Guccione %A Fengling Li %A Guillermo S. Cortez %A Ken Weichert %A Magdalena M. Szewczyk %A Mary M. Mader %A Masoud Vedadi %A Michael J. Grogan %A Mohammad S. Eram %A Peter J. Brown %A Robert M. Campbell %A Stephen Antonysamy %A Steven Kennedy %A Wayne P. Bocchinfuso %A Zahid Q. Bonday %J Archive of "ACS Medicinal Chemistry Letters". %D 2018 %R 10.1021/acsmedchemlett.8b00014 %K PRMT5 %K methyltransferase %K inhibitor %K splicing %K methylation %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047023/