%0 Journal Article
%T EXPRESSION OF IMMUNOGLOBULIN, GRANZYME-B AND PERFORIN AGAINST Ag85A AND Ag85B PROTEINS OF MYCOBACTERIUM TUBERCULOSIS IN BALB/C MICE
%A Fihiruddin
%A Ni Made Mertaniasih
%A Tri Wibawa
%A Wayan Tunas Artama
%J Archive of "African Journal of Infectious Diseases".
%D 2019
%R 10.21010/ajid.v13i2.2
%X Ag85 is a protein that may maintain survival of M. tuberculosis in intracellular parts of host cells and is considered as a virulence factor. The expression of Ag85 protein can stimulate proliferation and differentiation of B- cells and T-cells in patients with tuberculosis. This research aimed to determine the ability of Ag85A and Ag85B proteins in activating the response of antibodies, granzyme-B and perforin in Balb/c mice
%K Ag85A and Ag85B proteins
%K Immunoglobulin
%K granzyme B and perforin
%K TB Vaccine
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675963/