%0 Journal Article %T Two-stage revision after total knee arthroplasty %A Alessandro Beltrame %A Araldo Causero %A D. De Franceschi %A Enrico Daniele Di Benedetto %A Michele Mario Buttironi %A Paolo Di Benedetto %A Renato Gisonni %A Vanni Cainero %J Archive of "Acta Bio Medica : Atenei Parmensis". %D 2017 %R 10.23750/abm.v88i2-S.6519 %X Background and aim of the work: Periprosthetic knee infection is a complication associated with prosthetic failure; incidence change from 0,4-2% of primary total knee replacement and 5,6% in revisions; incidence is increasing over the years. Two-stage revision is the technique used in chronic infection. Aim of the work is to check success rate in our data. Methods: We analyzed retrospectively data of patients who undergone two stage revision surgery between 01/01/2010 to 31/12/2015. We made a clinical and radiological control after 1, 3, 6, 12, 24 months and we evaluate the outcome in December 2016. Results: Between 2010 and 2015 we treated 45 patients with two-stage revision. Mean follow-up was 3,4 years. Success rate is 89,9%. We had failure in 5 patients: everyone had knee surgery before first knee arthroplasty and Charlson Comorbidity Score was greater then 4 in 4 cases. Conclusions: Two stage revision can be considered a successful treatment in chronic periprosthetic knee infection. It has an optimal success rate, but it has some disadvantages as joint stiffness and pain in the interval between stages. This is a technique with two major surgery procedure with associated morbidity, discomfort, cost and prolonged stay in hospital. (www.actabiomedica.it %K knee %K periprosthetic %K infection %K two-stage %K revision %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178994/