%0 Journal Article %T PROCEEDINGS of the XVI CONGRESS OF THE ITALIAN SOCIETY OF MYOLOGY Lecce, Italy June 8-11, 2016 %J Archive of "Acta Myologica". %D 2016 %X It is well known that brain involvement is generally unusual in muscle disease, and should be considered in the algorithm of the differential diagnosis of myopathies. Classification of brain involvement in myopathies, excluding mitochondrial encephalomyopathies, can be classified for convenience in two main subgroups:1) those conditions with mental disabilities that are not associated with brain malformations; and 2) those that are associated with malformations or peculiar brain abnormalities, and can be detected by MRI %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105053/