%0 Journal Article %T Investigation of Immune-Regulatory Effects of Mageumsan Hot Spring via Protein Microarray In Vitro %A Dong Soo Yu %A Hyung Jin Hahn %A Jin-Wou Kim %A Jung Soo Kim %A Yeong Ho Kim %A Young Bok Lee %J Archive of "Annals of Dermatology". %D 2018 %R 10.5021/ad.2018.30.3.322 %X Empirical evidences for efficacy of hot spring (HS) water in inflammatory skin disorders have not been substantiated with sufficient, immunological ˇ°hard evidenceˇ±. Mageumsan HS water, characterized by its weakly-alkaline properties and low total dissolved solids content, has been known to alleviate various immune-inflammatory skin diseases, including atopic dermatitis (AD) %K Atopic dermatitis %K Hot spring water %K Immune-regulation %K Keratinocyte-derived cytokines/chemokines %K Protein array analysis %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929950/